Assay Detail
Binding
CHEMBL1816865
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation counting
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Inhibition | 2 | - | - |
| IC50 | 2 | 5.91 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL454440 | ANOMALIN A | — | 1 | 6.30 |
| CHEMBL466154 | NORLICHEXANTHONE | — | 1 | 5.52 |
| CHEMBL1812030 | MYROCIN D | — | 1 | - |
| CHEMBL516554 | MYROCIN A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL454440 | ANOMALIN A | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL466154 | NORLICHEXANTHONE | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1812030 | MYROCIN D | Inhibition | - | % | - | |
| CHEMBL516554 | MYROCIN A | Inhibition | - | % | - |