Assay Detail
Functional
CHEMBL1817047
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytoprotectant activity against L-buthionine-(S,R)-sulfoximine-induced cell death in Leigh syndrome patient fibroblasts assessed as increase of cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Fibroblast |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.52 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1812161 | VATIQUINONE | 3.0 | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1812161 | VATIQUINONE | EC50 | = | 30.0 | nM | 7.52 |