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Assay Detail

CHEMBL1817457

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H](-)-CGP12177 from human adrenergic beta1 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-1 adrenergic receptor (CHEMBL213)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Dolusić E, Larrieu P, Moineaux L, Stroobant V, Pilotte L, Colau D, Pochet L, Van den Eynde B, Masereel B, Wouters J, Frédérick R.
J Med Chem (2011) 54 : 5320 -5334
PubMed 21726069 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL24 ATENOLOL 4.0 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL24 ATENOLOL Ki = 170.0 nM 6.77