Assay Detail
Binding
CHEMBL1820883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rice alpha-glucosidase assessed as production of D-glucose using maltose as substrate after 10 to 30 mins by spectrophotometry
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryza sativa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.45 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | 7.52 |
| CHEMBL369297 | — | — | 1 | 5.37 |
| CHEMBL108084 | FAGOMINE | — | 1 | - |
| CHEMBL456583 | — | — | 1 | - |
| CHEMBL1818436 | — | — | 1 | - |
| CHEMBL1818437 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL369297 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL108084 | FAGOMINE | IC50 | = | 320000.0 | nM | - |
| CHEMBL456583 | — | IC50 | = | 120000.0 | nM | - |
| CHEMBL1818436 | — | IC50 | = | 188000.0 | nM | - |
| CHEMBL1818437 | — | IC50 | = | 980000.0 | nM | - |