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Assay Detail

CHEMBL1821334

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CCL5 binding to CCR5 expressed in CHO cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 5 (CHEMBL274)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents.
Haney KM, Zhang F, Arnatt CK, Yuan Y, Li G, Ware JL, Gewirtz DA, Zhang Y.
Bioorg Med Chem Lett (2011) 21 : 5159 -5163
PubMed 21820898 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.85 8.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41275 1 8.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41275 IC50 = 1.4 nM 8.85