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Assay Detail

CHEMBL1821383

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Functional
Cytotoxicity against human HL60 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Viridaphin A₁ glucoside, a green pigment possessing cytotoxic and antibacterial activity from the aphid Megoura crassicauda.
Horikawa M, Hoshiyama TS, Matsuzawa M, Shugyo T, Tanaka M, Suzuki S, Sato M, Ito T, Asakawa Y, Kaku H, Nishii T, Inai M, Takahashi S, Tsunoda T.
J Nat Prod (2011) 74 : 1812 -1816
PubMed 21830784 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.50 4.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1817674 VIRIDAPHIN A1 GLUCOSIDE 1 4.64
CHEMBL211501 ANTIMYCIN A 1 4.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1817674 VIRIDAPHIN A1 GLUCOSIDE IC50 = 23000.0 nM 4.64
CHEMBL211501 ANTIMYCIN A IC50 = 45000.0 nM 4.35