Assay Detail
Functional
CHEMBL1825341
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at rat recombinant TRPV2 receptor expressed in HEK293 cells assessed as inhibition of 3 uM lysophosphatidylcholine-induced stimulation of intracellular calcium level using Fluo4-AM dye based fluorimetric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily V member 2 (CHEMBL2863) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.73 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL497318 | CANNABIGEROL | 2.0 | 1 | 5.82 |
| CHEMBL1823117 | SESQUICANNABIGEROL | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL497318 | CANNABIGEROL | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL1823117 | SESQUICANNABIGEROL | IC50 | = | 2300.0 | nM | 5.64 |