Assay Detail
ADMET
CHEMBL1825481
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Cytotoxicity against CHO cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Indolin-2-one p38α inhibitors II: Lead optimisation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.63 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1825153 | — | — | 1 | 5.16 |
| CHEMBL1825149 | — | — | 1 | 4.80 |
| CHEMBL1825160 | — | — | 1 | 4.31 |
| CHEMBL1825156 | — | — | 1 | 4.24 |
| CHEMBL1825161 | — | — | 1 | - |
| CHEMBL1825162 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1825153 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL1825149 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL1825160 | — | IC50 | = | 49000.0 | nM | 4.31 |
| CHEMBL1825156 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL1825161 | — | IC50 | - | — | - | |
| CHEMBL1825162 | — | IC50 | - | — | - |