Assay Detail
Functional
CHEMBL1827784
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at Vibrio fischeri luxR receptor in absence of natural autoinducer
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aliivibrio fischeri |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transcriptional activator protein LuxR (CHEMBL5351) ↗| Type | SINGLE PROTEIN |
| Organism | Aliivibrio fischeri |
Publication
Medicinal chemistry as a conduit for the modulation of quorum sensing.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.46 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405298 | — | — | 1 | 6.46 |
| CHEMBL8463 | — | — | 1 | - |
| CHEMBL8755 | — | — | 1 | - |
| CHEMBL473592 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405298 | — | EC50 | = | 350.0 | nM | 6.46 |
| CHEMBL8463 | — | EC50 | - | — | - | |
| CHEMBL8755 | — | EC50 | - | — | - | |
| CHEMBL473592 | — | EC50 | - | — | - |