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Assay Detail

CHEMBL1831412

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of dephosphorylated glycogen phosphorylase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and biological activity of novel tiliroside derivants.
Qin N, Li CB, Jin MN, Shi LH, Duan HQ, Niu WY.
Eur J Med Chem (2011) 46 : 5189 -5195
PubMed 21856048 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.92 5.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL413552 QUERCETAGETIN 1 5.01
CHEMBL464107 6-HYDROXYLUTEOLIN 1 4.94
CHEMBL1829395 HYPOLAETIN 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL413552 QUERCETAGETIN IC50 = 9700.0 nM 5.01
CHEMBL464107 6-HYDROXYLUTEOLIN IC50 = 11600.0 nM 4.94
CHEMBL1829395 HYPOLAETIN IC50 = 15700.0 nM 4.80