Assay Detail
Binding
CHEMBL1837817
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to NPY5 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.22 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1836102 | — | — | 1 | 8.85 |
| CHEMBL17022 | — | — | 1 | 7.50 |
| CHEMBL19060 | BENEXTRAMINE | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1836102 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL17022 | — | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL19060 | BENEXTRAMINE | Ki | = | 5000.0 | nM | 5.30 |