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Assay Detail

CHEMBL1838784

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]BAY-38-7271 from recombinant human CB2 receptor expressed in CHO cells after 90 mins by scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands.
Teng H, Thakur GA, Makriyannis A.
Bioorg Med Chem Lett (2011) 21 : 5999 -6002
PubMed 21880487 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.34 7.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1354658 1 7.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1354658 Ki = 45.5 nM 7.34