Assay Detail
ADMET
CHEMBL1839009
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Cytostatic activity against human HeLaS3 cells after 48 hrs by XTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HeLa S3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of desmethoxy analogues of coruscanone A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.12 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1835081 | — | — | 1 | 5.31 |
| CHEMBL1835074 | — | — | 1 | 5.14 |
| CHEMBL1835084 | — | — | 1 | 5.14 |
| CHEMBL1835086 | — | — | 1 | 4.87 |
| CHEMBL216028 | CORUSCANONE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1835081 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1835074 | — | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL1835084 | — | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL1835086 | — | IC50 | = | 13500.0 | nM | 4.87 |
| CHEMBL216028 | CORUSCANONE A | IC50 | - | — | - |