Assay Detail
Functional
CHEMBL1839679
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Cytotoxicity against human PC3M cells by propidium iodide staining
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3M |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydrazidomycins, cytotoxic alkylhydrazides from Streptomycesatratus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.37 | 6.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1834207 | HYDRAZIDOMYCIN A | — | 1 | 6.98 |
| CHEMBL1834208 | HYDRAZIDOMYCIN B | — | 1 | 5.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1834207 | HYDRAZIDOMYCIN A | IC50 | = | 105.0 | nM | 6.98 |
| CHEMBL1834208 | HYDRAZIDOMYCIN B | IC50 | = | 1730.0 | nM | 5.76 |