Assay Detail
Functional
CHEMBL1839684
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Cytotoxicity against human RXF 393NL cells by propidium iodide staining
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RXF 393NL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Hydrazidomycins, cytotoxic alkylhydrazides from Streptomycesatratus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.46 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1834207 | HYDRAZIDOMYCIN A | — | 1 | 5.96 |
| CHEMBL1834208 | HYDRAZIDOMYCIN B | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1834207 | HYDRAZIDOMYCIN A | IC50 | = | 1110.0 | nM | 5.96 |
| CHEMBL1834208 | HYDRAZIDOMYCIN B | IC50 | = | 11000.0 | nM | 4.96 |