Assay Detail
ADMET
CHEMBL1908259
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Mechanism based inhibition of rat cytochrome P450 CYP1A2 measured by zolmitriptan metabolism
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.24 | 4.24 |
| kinact | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL814 | FLUVOXAMINE | 4.0 | 2 | 4.24 |