Assay Detail
Binding
CHEMBL1912893
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.62 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL205982 | — | — | 1 | 6.66 |
| CHEMBL1911831 | — | — | 1 | 6.57 |
| CHEMBL461161 | — | — | 1 | - |
| CHEMBL505422 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL205982 | — | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL1911831 | — | Ki | = | 270.0 | nM | 6.57 |
| CHEMBL461161 | — | Ki | - | — | - | |
| CHEMBL505422 | — | Ki | - | — | - |