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Assay Detail

CHEMBL1913675

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonist activity at FP receptor in mouse myometrial strip assessed as inhibition of PGF-2alpha-induced contractions
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prostaglandin F2-alpha receptor (CHEMBL5000)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Targeting the prostaglandin F2α receptor for preventing preterm labor with azapeptide tocolytics.
Bourguet CB, Goupil E, Tassy D, Hou X, Thouin E, Polyak F, Hébert TE, Claing A, Laporte SA, Chemtob S, Lubell WD.
J Med Chem (2011) 54 : 6085 -6097
PubMed 21774512 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.89 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1910324 1 7.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1910324 IC50 = 13.0 nM 7.89