Assay Detail
Binding
CHEMBL1920542
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-prazosin from alpha 1 receptor in rat cortex by liquid scintillation counting
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.93 | 7.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1917360 | — | — | 1 | 7.04 |
| CHEMBL1917359 | — | — | 1 | 6.81 |
| CHEMBL1917354 | — | — | 1 | - |
| CHEMBL1917355 | — | — | 1 | - |
| CHEMBL1917356 | — | — | 1 | - |
| CHEMBL1917357 | — | — | 1 | - |
| CHEMBL1917358 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1917360 | — | Ki | = | 92.0 | nM | 7.04 |
| CHEMBL1917359 | — | Ki | = | 155.0 | nM | 6.81 |
| CHEMBL1917354 | — | Ki | - | — | - | |
| CHEMBL1917355 | — | Ki | - | — | - | |
| CHEMBL1917356 | — | Ki | - | — | - | |
| CHEMBL1917357 | — | Ki | - | — | - | |
| CHEMBL1917358 | — | Ki | - | — | - |