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Assay Detail

CHEMBL1925866

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human U87MG cells after 24 to 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U-87MG ATCC
Confidence 1 — Organism
Curated By Autocuration

Publication

Tyrphostin-like compounds with ubiquitin modulatory activity as possible therapeutic agents for multiple myeloma.
Peng Z, Pal A, Han D, Wang S, Maxwell D, Levitzki A, Talpaz M, Donato NJ, Bornmann W.
Bioorg Med Chem (2011) 19 : 7194 -7204
PubMed 22036213 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.25 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1923234 WP 1066 2.0 1 5.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1923234 WP 1066 IC50 = 5600.0 nM 5.25