Assay Detail
Functional
CHEMBL1930617
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human KBVIN cells after 3 days by SRB assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KBVIN |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 13 | 5.16 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1928921 | — | — | 1 | 5.80 |
| CHEMBL1928923 | — | — | 1 | 5.68 |
| CHEMBL1928924 | — | — | 1 | 5.29 |
| CHEMBL1928925 | — | — | 1 | 5.15 |
| CHEMBL1929082 | — | — | 1 | 4.96 |
| CHEMBL1929083 | — | — | 1 | 4.76 |
| CHEMBL1928922 | — | — | 1 | 4.47 |
| CHEMBL1928926 | — | — | 1 | - |
| CHEMBL1928928 | — | — | 1 | - |
| CHEMBL1926708 | — | — | 1 | - |
| CHEMBL1928929 | — | — | 1 | - |
| CHEMBL1929084 | — | — | 1 | - |
| CHEMBL1929085 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1928921 | — | EC50 | = | 1570.0 | nM | 5.80 |
| CHEMBL1928923 | — | EC50 | = | 2070.0 | nM | 5.68 |
| CHEMBL1928924 | — | EC50 | = | 5140.0 | nM | 5.29 |
| CHEMBL1928925 | — | EC50 | = | 7020.0 | nM | 5.15 |
| CHEMBL1929082 | — | EC50 | = | 11040.0 | nM | 4.96 |
| CHEMBL1929083 | — | EC50 | = | 17210.0 | nM | 4.76 |
| CHEMBL1928922 | — | EC50 | = | 33970.0 | nM | 4.47 |
| CHEMBL1928926 | — | EC50 | - | — | - | |
| CHEMBL1928928 | — | EC50 | - | — | - | |
| CHEMBL1926708 | — | EC50 | - | — | - | |
| CHEMBL1928929 | — | EC50 | - | — | - | |
| CHEMBL1929084 | — | EC50 | - | — | - | |
| CHEMBL1929085 | — | EC50 | - | — | - |