Assay Detail
Functional
CHEMBL1937037
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Anticancer activity against human UMRC2 cells after 96 hrs by SRB assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | UMRC2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, anticancer activity and pharmacokinetic analysis of 1-[(substituted 2-alkoxyquinoxalin-3-yl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.25 | 8.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1934205 | — | — | 1 | 8.21 |
| CHEMBL1934203 | — | — | 1 | 7.85 |
| CHEMBL1934204 | — | — | 1 | 7.35 |
| CHEMBL1934199 | — | — | 1 | 7.24 |
| CHEMBL1934202 | — | — | 1 | 7.04 |
| CHEMBL1934200 | — | — | 1 | 6.57 |
| CHEMBL1934201 | — | — | 1 | 6.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1934205 | — | IC50 | = | 6.1 | nM | 8.21 |
| CHEMBL1934203 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL1934204 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL1934199 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL1934202 | — | IC50 | = | 92.0 | nM | 7.04 |
| CHEMBL1934200 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL1934201 | — | IC50 | = | 320.0 | nM | 6.50 |