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Assay Detail

CHEMBL1937240

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat intact neuron FAAH
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL3229)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.
Rusch M, Zahov S, Vetter IR, Lehr M, Hedberg C.
Bioorg Med Chem (2012) 20 : 1100 -1112
PubMed 22196515 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL184238 URB-597 1.0 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL184238 URB-597 IC50 = 0.5 nM 9.30