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Assay Detail

CHEMBL1937244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FAAH
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL2243)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.
Rusch M, Zahov S, Vetter IR, Lehr M, Hedberg C.
Bioorg Med Chem (2012) 20 : 1100 -1112
PubMed 22196515 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.39 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL90308 1 6.85
CHEMBL93675 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL90308 Ki = 140.0 nM 6.85
CHEMBL93675 Ki = 1200.0 nM 5.92