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Assay Detail

CHEMBL1937759

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at dog PPARalpha
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Canis lupus familiaris
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL2847)
Type SINGLE PROTEIN
Organism Canis lupus familiaris

Publication

Discovery of cyclic amine-substituted benzoic acids as PPARα agonists.
Nomura M, Yumoto K, Shinozaki T, Isogai S, Takano Y, Murakami K.
Bioorg Med Chem Lett (2012) 22 : 334 -338
PubMed 22133631 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.72 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1934476 1 6.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1934476 EC50 = 190.0 nM 6.72