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Assay Detail

CHEMBL1937890

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 17beta-HSD3 in mouse testes homogenate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Tissue Testis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

17-beta-hydroxysteroid dehydrogenase type 3 (CHEMBL1932905)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors.
Harada K, Kubo H, Tanaka A, Nishioka K.
Bioorg Med Chem Lett (2012) 22 : 504 -507
PubMed 22137341 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1934493 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1934493 IC50 = 40.0 nM 7.40