Assay Detail
Binding
CHEMBL1942535
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Inhibition of KDM4A
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Lysine demethylases inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.18 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1435274 | — | — | 1 | 5.77 |
| CHEMBL1229308 | — | — | 1 | 5.52 |
| CHEMBL583959 | BIS(PYRROLIDINYLTHIOCARBONYL)DISULFIDE | — | 1 | 5.48 |
| CHEMBL1938900 | — | — | 1 | 5.37 |
| CHEMBL602503 | — | — | 1 | 4.92 |
| CHEMBL1614745 | — | — | 1 | 4.62 |
| CHEMBL1615211 | — | — | 1 | 4.58 |
| CHEMBL90852 | N-OXALYLGLYCINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1435274 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1229308 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL583959 | BIS(PYRROLIDINYLTHIOCARBONYL)DISULFIDE | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL1938900 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL602503 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL1614745 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL1615211 | — | IC50 | = | 26000.0 | nM | 4.58 |
| CHEMBL90852 | N-OXALYLGLYCINE | IC50 | = | 250000.0 | nM | - |