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Assay Detail

CHEMBL1942536

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of KDM2A
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Lysine-specific demethylase 2A (CHEMBL1938210)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Lysine demethylases inhibitors.
Suzuki T, Miyata N.
J Med Chem (2011) 54 : 8236 -8250
PubMed 21955276 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.32 4.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1615211 1 4.32
CHEMBL1614745 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1615211 IC50 = 48000.0 nM 4.32
CHEMBL1614745 IC50 = 106000.0 nM -