Assay Detail
Functional
CHEMBL1947355
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Antioxidant activity assessed as NADH oxidation-induced superoxide radical scavenging activity after 20 mins
11
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel inhibitors of nitric oxide synthase with antioxidant properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.21 | 4.42 |
| Activity | 4 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1945914 | — | — | 2 | 4.42 |
| CHEMBL1945752 | — | — | 2 | 4.18 |
| CHEMBL447987 | — | — | 1 | 4.16 |
| CHEMBL1529996 | — | — | 2 | 4.07 |
| CHEMBL1946359 | — | — | 1 | - |
| CHEMBL162549 | — | — | 1 | - |
| CHEMBL1946353 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1945914 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL1945752 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL447987 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL1529996 | — | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL1946359 | — | IC50 | = | 185000.0 | nM | - |
| CHEMBL162549 | — | IC50 | = | 165000.0 | nM | - |
| CHEMBL1529996 | — | Activity | - | — | - | |
| CHEMBL1946353 | — | Activity | - | — | - | |
| CHEMBL1945914 | — | Activity | - | — | - | |
| CHEMBL1945752 | — | Activity | - | — | - | |
| CHEMBL1946353 | — | IC50 | > | 100000.0 | nM | - |