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Assay Detail

CHEMBL1948967

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse Colon 26 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Colon 26
Confidence 1 — Organism
Curated By Autocuration

Target

Colon 26 (CHEMBL614466)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.
Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G.
J Med Chem (2012) 55 : 475 -488
PubMed 22136312 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.14 8.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL324397 1 8.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL324397 IC50 = 7.2 nM 8.14