Assay Detail
Functional
CHEMBL1952575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human S1P5R
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.58 | 9.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL366208 | FTY720-P | -1.0 | 1 | 9.47 |
| CHEMBL1951588 | — | — | 1 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL366208 | FTY720-P | EC50 | = | 0.34 | nM | 9.47 |
| CHEMBL1951588 | — | EC50 | = | 21.0 | nM | 7.68 |