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Assay Detail

CHEMBL1958985

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Binding
Inhibition of AXL
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tyrosine-protein kinase receptor UFO (CHEMBL4895)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

VX-322: a novel dual receptor tyrosine kinase inhibitor for the treatment of acute myelogenous leukemia.
Heidary DK, Huang G, Boucher D, Ma J, Forster C, Grey R, Xu J, Arnost M, Choquette D, Chen G, Zhou JH, Yao YM, Ball ED, Namchuk M, Davies RJ, Henkel G.
J Med Chem (2012) 55 : 725 -734
PubMed 22221201 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1835870 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1835870 Ki = 40.0 nM 7.40