Assay Detail
Binding
CHEMBL1960166
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Inhibition of rat DAT
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent dopamine transporter (CHEMBL338) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Wake-promoting agents: search for next generation modafinil: part I.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.83 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1956397 | — | — | 1 | 6.22 |
| CHEMBL1373 | MODAFINIL | 4.0 | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1956397 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL1373 | MODAFINIL | IC50 | = | 3700.0 | nM | 5.43 |