Sodium-dependent dopamine transporter · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P23977. Use UniProt P23977 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23977 as the stable identity anchor, then attach disease evidence before program review.
Sodium-dependent dopamine transporter
Review this target as Sodium-dependent dopamine transporter, mapped to UniProt P23977. Sequence length is 619 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sodium-dependent dopamine transporter as ChEMBL target CHEMBL338, mapped to UniProt P23977. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sodium-dependent dopamine transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P23977 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sodium-dependent dopamine transporter |
| UniProt Accession | P23977 |
| Component Type | Protein |
| Sequence Length | 619 aa |
Sodium-dependent dopamine transporter
Review this target as Sodium-dependent dopamine transporter, mapped to UniProt P23977. Sequence length is 619 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL36720 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL113621 | 10.4 | Ki | 0.04 | Preclinical |
| CHEMBL418190 | 10.37 | IC50 | 0.043 | Preclinical |
| CHEMBL281594 | 10.22 | Ki | 0.06 | Clinical |
| CHEMBL168455 | 10.11 | IC50 | 0.077 | Preclinical |
| CHEMBL169117 | 10.07 | IC50 | 0.085 | Preclinical |
| CHEMBL544971 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL3093268 | 9.89 | Ki | 0.13 | Preclinical |
| CHEMBL39990 | 9.89 | IC50 | 0.13 | Preclinical |
| CHEMBL320427 | 9.85 | Ki | 0.14 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 147 | 818 | 7.0 |
| tissue-based format | 117 | 1,051 | 6.9 |
| cell membrane format | 61 | 537 | 7.1 |
| assay format | 54 | 428 | 7.2 |
| subcellular format | 54 | 562 | 6.5 |
| cell-based format | 10 | 21 | 5.5 |
| organism-based format | 1 | 35 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 27 | 106 | 7.0 |
| tissue-based format | 26 | 203 | 6.4 |
| organism-based format | 8 | 38 | 7.7 |
| subcellular format | 8 | 112 | 6.8 |
| cell-based format | 1 | 26 | 5.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 1 | 5.1 |