Assay Detail
Functional
CHEMBL1960338
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Cytotoxicity against Chinese hamster V79 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | V79 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Disparate SAR data of griseofulvin analogues for the dermatophytes Trichophyton mentagrophytes, T. rubrum, and MDA-MB-231 cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.63 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL522763 | — | — | 1 | 6.16 |
| CHEMBL562 | GRISEOFULVIN | 4.0 | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL522763 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL562 | GRISEOFULVIN | IC50 | = | 8000.0 | nM | 5.10 |