Assay Detail
Functional
CHEMBL1961315
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 30 mins measured 24 hrs post LPS challenge by Griess method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.51 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL256147 | TILARGININE | 3.0 | 1 | 4.71 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.51 |
| CHEMBL1957217 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL256147 | TILARGININE | IC50 | = | 19700.0 | nM | 4.71 |
| CHEMBL165 | RESVERATROL | IC50 | = | 30710.0 | nM | 4.51 |
| CHEMBL1957217 | — | IC50 | = | 47800.0 | nM | 4.32 |