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Assay Detail

CHEMBL1963711

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: EEF2K
ChEMBL ↗
405
Total Activities
398
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Eukaryotic elongation factor 2 kinase (CHEMBL5026) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 405 5.81 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1988173 — — 1 7.10
CHEMBL1989805 — — 1 6.40
CHEMBL2006263 — — 1 6.10
CHEMBL1977874 — — 1 6.10
CHEMBL1969506 — — 1 6.00
CHEMBL1969042 — — 1 6.00
CHEMBL1987793 — — 1 5.90
CHEMBL2001751 — — 1 5.90
CHEMBL2004544 — — 1 5.80
CHEMBL1974803 — — 1 5.80
CHEMBL1974157 — — 1 5.70
CHEMBL1996831 — — 1 5.60
CHEMBL2005631 — — 1 5.60
CHEMBL1983195 — — 1 5.60
CHEMBL1984039 — — 1 5.60
CHEMBL1972125 — — 1 5.50
CHEMBL1986328 — — 1 5.50
CHEMBL2004365 — — 1 5.50
CHEMBL1991063 — — 1 5.50
CHEMBL1998611 — — 1 5.50
CHEMBL1973860 — — 1 5.40
CHEMBL1967887 — — 1 -
CHEMBL213505 — — 1 -
CHEMBL2000568 — — 1 -
CHEMBL2000335 — — 1 -
CHEMBL1084546 PF-00562271 1.0 1 -
CHEMBL1987034 — — 1 -
CHEMBL1993941 — — 1 -
CHEMBL377383 — — 1 -
CHEMBL2005886 — — 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1988173 — Ki = 79.43 nM 7.10
CHEMBL1989805 — Ki = 398.11 nM 6.40
CHEMBL1977874 — Ki = 794.33 nM 6.10
CHEMBL2006263 — Ki = 794.33 nM 6.10
CHEMBL1969042 — Ki = 1000.0 nM 6.00
CHEMBL1969506 — Ki = 1000.0 nM 6.00
CHEMBL2001751 — Ki = 1258.93 nM 5.90
CHEMBL1987793 — Ki = 1258.93 nM 5.90
CHEMBL2004544 — Ki = 1584.89 nM 5.80
CHEMBL1974803 — Ki = 1584.89 nM 5.80
CHEMBL1974157 — Ki = 1995.26 nM 5.70
CHEMBL1984039 — Ki = 2511.89 nM 5.60
CHEMBL2005631 — Ki = 2511.89 nM 5.60
CHEMBL1983195 — Ki = 2511.89 nM 5.60
CHEMBL1996831 — Ki = 2511.89 nM 5.60
CHEMBL1972125 — Ki = 3162.28 nM 5.50
CHEMBL1986328 — Ki = 3162.28 nM 5.50
CHEMBL1998611 — Ki = 3162.28 nM 5.50
CHEMBL1991063 — Ki = 3162.28 nM 5.50
CHEMBL2004365 — Ki = 3162.28 nM 5.50
CHEMBL1973860 — Ki = 3981.07 nM 5.40
CHEMBL1982466 — Ki > 3981.07 nM -
CHEMBL1981047 — Ki > 3981.07 nM -
CHEMBL306380 — Ki > 3981.07 nM -
CHEMBL1995740 — Ki > 3981.07 nM -
CHEMBL1964413 — Ki > 3981.07 nM -
CHEMBL402846 — Ki > 3981.07 nM -
CHEMBL1990415 — Ki > 3981.07 nM -
CHEMBL1966087 — Ki > 3981.07 nM -
CHEMBL2007064 — Ki > 3981.07 nM -
CHEMBL1964692 — Ki > 3981.07 nM -
CHEMBL1970735 — Ki > 3981.07 nM -
CHEMBL117697 — Ki > 3981.07 nM -
CHEMBL1976240 — Ki > 3981.07 nM -
CHEMBL1970522 — Ki > 3981.07 nM -
CHEMBL262433 — Ki > 3981.07 nM -
CHEMBL1993548 — Ki > 3981.07 nM -
CHEMBL271381 — Ki > 3981.07 nM -
CHEMBL1981720 — Ki > 3981.07 nM -
CHEMBL2006276 — Ki > 3981.07 nM -
CHEMBL1727312 — Ki > 3981.07 nM -
CHEMBL1970314 — Ki > 3981.07 nM -
CHEMBL256835 — Ki > 3981.07 nM -
CHEMBL1990885 — Ki > 3981.07 nM -
CHEMBL1990821 — Ki > 2511.89 nM -
CHEMBL1990884 — Ki > 3981.07 nM -
CHEMBL116070 — Ki > 3981.07 nM -
CHEMBL468280 — Ki > 3981.07 nM -
CHEMBL2004892 — Ki > 3981.07 nM -
CHEMBL1965988 — Ki > 3981.07 nM -