Assay Detail
Functional
CHEMBL2014017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antinociceptive activity in sc dosed Sprague-Dawley rat Freund's complete adjuvant model of inflammatory pain assessed as effect on paw withdrawal threshold administered 96 hrs post FCA-challenge
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of P2X3 selective antagonists for the treatment of chronic pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| EC50 | 1 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2011112 | — | — | 2 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2011112 | — | EC50 | = | 199.0 | nM | 6.70 |
| CHEMBL2011112 | — | Activity | - | — | - |