Assay Detail
Binding
CHEMBL2019476
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Displacement of [125I]-OVTA from prairie vole Oxytocin receptor after 72 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Microtus ochrogaster |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.28 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017869 | — | — | 1 | 8.54 |
| CHEMBL2017867 | — | — | 1 | 8.44 |
| CHEMBL2017868 | — | — | 1 | 8.38 |
| CHEMBL2017979 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017869 | — | Ki | = | 2.9 | nM | 8.54 |
| CHEMBL2017867 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL2017868 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL2017979 | — | Ki | = | 18.0 | nM | 7.75 |