Assay Detail
Binding
CHEMBL2019481
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Displacement of [3H]-AVP from human vasopressin V2 receptor after 1.5 hrs by liquid scintillation counting
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.82 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017868 | — | — | 1 | 6.24 |
| CHEMBL2017867 | — | — | 1 | 5.85 |
| CHEMBL2017869 | — | — | 1 | 5.75 |
| CHEMBL2017979 | — | — | 1 | 5.43 |
| CHEMBL2017980 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017868 | — | Ki | = | 580.0 | nM | 6.24 |
| CHEMBL2017867 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL2017869 | — | Ki | = | 1800.0 | nM | 5.75 |
| CHEMBL2017979 | — | Ki | = | 3700.0 | nM | 5.43 |
| CHEMBL2017980 | — | Ki | > | 1000.0 | nM | - |