Assay Detail
Functional
CHEMBL2019566
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Cytotoxicity against human XF498 cells after 48 hrs by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | XF498 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic cytochalasins from the endozoic fungus Phoma sp. of the giant jellyfish Nemopilema nomurai.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.12 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.82 |
| CHEMBL411729 | CYTOCHALASIN B | — | 1 | 5.63 |
| CHEMBL2018715 | — | — | 1 | 4.91 |
| CHEMBL2018716 | DEOXAPHOMIN B | — | 1 | - |
| CHEMBL2018717 | DEOXAPHOMIN C | — | 1 | - |
| CHEMBL2018718 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL411729 | CYTOCHALASIN B | IC50 | = | 2360.0 | nM | 5.63 |
| CHEMBL2018715 | — | IC50 | = | 12290.0 | nM | 4.91 |
| CHEMBL2018716 | DEOXAPHOMIN B | IC50 | - | — | - | |
| CHEMBL2018717 | DEOXAPHOMIN C | IC50 | - | — | - | |
| CHEMBL2018718 | — | IC50 | - | — | - |