Assay Detail
Binding
CHEMBL2025259
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Aurora B
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.91 | 7.91 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2022968 | DUBERMATINIB | 2.0 | 1 | 7.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2022968 | DUBERMATINIB | IC50 | = | 12.4 | nM | 7.91 |