Assay Detail
Binding
CHEMBL2033180
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Inhibition of human recombinant PYK2 by ESI-MS analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of binding specificity-determining features in protein families.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.93 | 7.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL261641 | — | — | 1 | 7.98 |
| CHEMBL76904 | TYRPHOSTIN 23 | — | 1 | 6.79 |
| CHEMBL306498 | ALOISINE | — | 1 | 6.03 |
| CHEMBL319467 | — | — | 1 | - |
| CHEMBL411491 | — | — | 1 | - |
| CHEMBL505177 | SCYTONEMIN | — | 1 | - |
| CHEMBL407391 | DIMETHYLADENINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL261641 | — | Ki | = | 10.47 | nM | 7.98 |
| CHEMBL76904 | TYRPHOSTIN 23 | Ki | = | 162.18 | nM | 6.79 |
| CHEMBL306498 | ALOISINE | Ki | = | 933.25 | nM | 6.03 |
| CHEMBL319467 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL411491 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL505177 | SCYTONEMIN | Ki | > | 10000.0 | nM | - |
| CHEMBL407391 | DIMETHYLADENINE | Ki | > | 10000.0 | nM | - |