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Assay Detail

CHEMBL2033842

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of mtronidazole-resistant Trichomonas vaginalis after 24 hrs by hemocytometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Trichomonas vaginalis
Confidence 1 — Organism
Curated By Autocuration

Target

Trichomonas vaginalis (CHEMBL612884)
Type ORGANISM
Organism Trichomonas vaginalis

Publication

S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
Shokar A, Au A, An SH, Tong E, Garza G, Zayas J, Wnuk SF, Land KM.
Bioorg Med Chem Lett (2012) 22 : 4203 -4205
PubMed 22579483 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.34 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL137 METRONIDAZOLE 4.0 1 6.68
CHEMBL2032002 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL137 METRONIDAZOLE IC50 = 210.0 nM 6.68
CHEMBL2032002 IC50 = 100000.0 nM 4.00