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Target Snapshot

CHEMBL612884 Target Snapshot

Trichomonas vaginalis · ORGANISM · Trichomonas vaginalis

Back to Search Search this target Browse approvals Evidence Card
1,399Compounds
269Assays
15Approved Drugs
933.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Trichomonas vaginalis as ChEMBL target CHEMBL612884. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Trichomonas vaginalis
ORGANISM · Trichomonas vaginalis
As of 2026-09-14
ChEMBL target ID
CHEMBL612884
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Trichomonas vaginalis still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NameTrichomonas vaginalis
Target TypeORGANISM
OrganismTrichomonas vaginalis
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelTrichomonas vaginalis
UniProt AccessionN/A

Trichomonas vaginalis

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Trichomonas vaginalis.

Review nameTrichomonas vaginalis
OrganismTrichomonas vaginalis
Clinical Profile

Clinical Phase Distribution

15
Approved
3
Phase II
Assay Mix

Activity Type Distribution

IC50873.0
EC5060.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL227370 8.7 IC50 1.995 Preclinical
CHEMBL3220969 8.52 IC50 3.0 Preclinical
CHEMBL1080623 8.22 IC50 6.0 Preclinical
CHEMBL3114401 8.0 IC50 10.0 Preclinical
CHEMBL3220968 8.0 IC50 10.0 Preclinical
CHEMBL3220963 7.99 IC50 10.23 Preclinical
CHEMBL4210015 7.92 IC50 12.0 Preclinical
CHEMBL4217508 7.88 IC50 13.2 Preclinical
CHEMBL1170756 7.8 IC50 16.0 Preclinical
CHEMBL459380 7.72 IC50 18.9 Preclinical
Distribution

pChEMBL Value Distribution

75
5.0
52
5.5
45
6.0
97
6.5
55
7.0
26
7.5
7
8.0
6
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

SECNIDAZOLE
CHEMBL498847
Approved 2017
Properties Compare Identifier
NITAZOXANIDE
CHEMBL1401
Approved 2002
Properties Compare Identifier
PANTOPRAZOLE
CHEMBL1502
Approved 2000
Properties Compare Identifier
RABEPRAZOLE
CHEMBL1219
Approved 1999
Properties Compare Identifier
LANSOPRAZOLE
CHEMBL480
Approved 1995
Properties Compare Identifier
OMEPRAZOLE
CHEMBL1503
Approved 1989
Properties Compare Identifier
METRONIDAZOLE
CHEMBL137
Approved 1963
Properties Compare Identifier
Assay Landscape

Assay Landscape

269
Total Assays
446
Tested Compounds
1
Assay Types
Functional — 269 assays, 446 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 253 403 5.9
assay format 16 43 5.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine