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Assay Detail

CHEMBL2038185

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of CYP1A2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cytochrome P450 1A2 (CHEMBL3356)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The design, synthesis, and biological evaluation of PIM kinase inhibitors.
Tsuhako AL, Brown DS, Koltun ES, Aay N, Arcalas A, Chan V, Du H, Engst S, Franzini M, Galan A, Huang P, Johnston S, Kane B, Kim MH, Laird AD, Lin R, Mock L, Ngan I, Pack M, Stott G, Stout TJ, Yu P, Zaharia C, Zhang W, Zhou P, Nuss JM, Kearney PC, Xu W.
Bioorg Med Chem Lett (2012) 22 : 3732 -3738
PubMed 22542012 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.29 5.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2030386 1 5.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2030386 IC50 = 5100.0 nM 5.29