Assay Detail
Functional
CHEMBL2039197
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against rat RIE cells expressing TRKA and NGF
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | RIE |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.77 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2037226 | — | — | 1 | 7.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2037226 | — | IC50 | = | 17.0 | nM | 7.77 |