Assay Detail
Binding
CHEMBL2039382
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Inhibition of human TAS2R31 receptor expressed in HEK293T cells overexpressing chimeric G-protein alpha-subunit
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The relevance of higher plants in lead compound discovery programs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.42 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL490162 | — | — | 1 | 5.70 |
| CHEMBL210692 | — | — | 1 | 5.60 |
| CHEMBL448297 | SAKURANETIN | — | 1 | 5.44 |
| CHEMBL487601 | JACEOSIDINE | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL490162 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL210692 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL448297 | SAKURANETIN | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL487601 | JACEOSIDINE | IC50 | = | 11300.0 | nM | 4.95 |