Assay Detail
Functional
CHEMBL2040180
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Human respiratory syncytial virus A2 ATCC VR-1540 infected in african green monkey Vero-76 cells assessed as reduction in viral plaque after 5 days by crystal violet staining
56
Total Activities
56
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human respiratory syncytial virus A2 |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
5-acetyl-2-arylbenzimidazoles as antiviral agents. Part 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 56 | 6.04 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2037274 | — | — | 1 | 7.52 |
| CHEMBL2037273 | — | — | 1 | 7.52 |
| CHEMBL2037272 | — | — | 1 | 6.00 |
| CHEMBL564201 | 6-AZAURIDINE | — | 1 | 5.92 |
| CHEMBL2037243 | — | — | 1 | 4.70 |
| CHEMBL2037241 | — | — | 1 | 4.60 |
| CHEMBL2037253 | — | — | 1 | - |
| CHEMBL2037263 | — | — | 1 | - |
| CHEMBL2037254 | — | — | 1 | - |
| CHEMBL2037255 | — | — | 1 | - |
| CHEMBL2037256 | — | — | 1 | - |
| CHEMBL2037257 | — | — | 1 | - |
| CHEMBL2035005 | — | — | 1 | - |
| CHEMBL2037258 | — | — | 1 | - |
| CHEMBL2037259 | — | — | 1 | - |
| CHEMBL2037260 | — | — | 1 | - |
| CHEMBL2037261 | — | — | 1 | - |
| CHEMBL2037262 | — | — | 1 | - |
| CHEMBL2037240 | — | — | 1 | - |
| CHEMBL2037264 | — | — | 1 | - |
| CHEMBL2037252 | — | — | 1 | - |
| CHEMBL2037251 | — | — | 1 | - |
| CHEMBL2037250 | — | — | 1 | - |
| CHEMBL2037249 | — | — | 1 | - |
| CHEMBL2037248 | — | — | 1 | - |
| CHEMBL2037247 | — | — | 1 | - |
| CHEMBL2037246 | — | — | 1 | - |
| CHEMBL2037245 | — | — | 1 | - |
| CHEMBL2037244 | — | — | 1 | - |
| CHEMBL2037239 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2037274 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL2037273 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL2037272 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL564201 | 6-AZAURIDINE | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL2037243 | — | EC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL2037241 | — | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL2037162 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037262 | — | EC50 | - | — | - | |
| CHEMBL1093220 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL1092985 | — | EC50 | - | — | - | |
| CHEMBL2037161 | — | EC50 | - | — | - | |
| CHEMBL2037160 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037159 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037169 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2035004 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037263 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037174 | — | EC50 | - | — | - | |
| CHEMBL2037163 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037164 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037165 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037166 | — | EC50 | - | — | - | |
| CHEMBL2037167 | — | EC50 | - | — | - | |
| CHEMBL2037168 | — | EC50 | - | — | - | |
| CHEMBL2037242 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037170 | — | EC50 | - | — | - | |
| CHEMBL2037171 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037172 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037173 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037264 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037239 | — | EC50 | - | — | - | |
| CHEMBL2037244 | — | EC50 | > | 30000.0 | nM | - |
| CHEMBL2037245 | — | EC50 | > | 70000.0 | nM | - |
| CHEMBL2037246 | — | EC50 | - | — | - | |
| CHEMBL2037247 | — | EC50 | - | — | - | |
| CHEMBL2037248 | — | EC50 | - | — | - | |
| CHEMBL2037249 | — | EC50 | - | — | - | |
| CHEMBL2037250 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037251 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037252 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037261 | — | EC50 | - | — | - | |
| CHEMBL2037240 | — | EC50 | - | — | - | |
| CHEMBL2037253 | — | EC50 | - | — | - | |
| CHEMBL2037254 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037255 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037256 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037257 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL2035005 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037258 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2037259 | — | EC50 | > | 40000.0 | nM | - |
| CHEMBL2037260 | — | EC50 | > | 20000.0 | nM | - |