Assay Detail
Functional
CHEMBL2044645
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human Lipo cells after 96 hrs by SRB assay
35
Total Activities
35
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Lipo |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel (E) stilbene-based antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 35 | 5.25 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2043264 | — | — | 1 | 7.52 |
| CHEMBL2043265 | — | — | 1 | 6.68 |
| CHEMBL419378 | — | — | 1 | 6.40 |
| CHEMBL2043266 | — | — | 1 | 6.21 |
| CHEMBL2043267 | — | — | 1 | 6.19 |
| CHEMBL1817670 | — | — | 1 | 5.85 |
| CHEMBL2043270 | — | — | 1 | 5.81 |
| CHEMBL2043268 | — | — | 1 | 5.70 |
| CHEMBL2043269 | — | — | 1 | 5.67 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | — | 1 | 5.54 |
| CHEMBL2043271 | — | — | 1 | 5.48 |
| CHEMBL242396 | — | — | 1 | 5.30 |
| CHEMBL83 | TAMOXIFEN | 4.0 | 1 | 5.06 |
| CHEMBL2043274 | — | — | 1 | 4.91 |
| CHEMBL2043276 | — | — | 1 | 4.88 |
| CHEMBL83527 | PTEROSTILBENE | 2.0 | 1 | 4.85 |
| CHEMBL2043273 | — | — | 1 | 4.85 |
| CHEMBL2043272 | — | — | 1 | 4.82 |
| CHEMBL383273 | — | — | 1 | 4.81 |
| CHEMBL2043275 | — | — | 1 | 4.81 |
| CHEMBL2043277 | — | — | 1 | 4.78 |
| CHEMBL2043279 | — | — | 1 | 4.77 |
| CHEMBL1817794 | — | — | 1 | 4.76 |
| CHEMBL1817800 | — | — | 1 | 4.74 |
| CHEMBL1817790 | — | — | 1 | 4.70 |
| CHEMBL1817793 | — | — | 1 | 4.67 |
| CHEMBL2043278 | — | — | 1 | 4.66 |
| CHEMBL1817791 | — | — | 1 | 4.63 |
| CHEMBL1817804 | — | — | 1 | 4.62 |
| CHEMBL1817796 | — | — | 1 | 4.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2043264 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL2043265 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL419378 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL2043266 | — | IC50 | = | 610.0 | nM | 6.21 |
| CHEMBL2043267 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL1817670 | — | IC50 | = | 1410.0 | nM | 5.85 |
| CHEMBL2043270 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL2043268 | — | IC50 | = | 1980.0 | nM | 5.70 |
| CHEMBL2043269 | — | IC50 | = | 2120.0 | nM | 5.67 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | IC50 | = | 2860.0 | nM | 5.54 |
| CHEMBL2043271 | — | IC50 | = | 3280.0 | nM | 5.48 |
| CHEMBL242396 | — | IC50 | = | 4980.0 | nM | 5.30 |
| CHEMBL83 | TAMOXIFEN | IC50 | = | 8640.0 | nM | 5.06 |
| CHEMBL2043274 | — | IC50 | = | 12450.0 | nM | 4.91 |
| CHEMBL2043276 | — | IC50 | = | 13160.0 | nM | 4.88 |
| CHEMBL83527 | PTEROSTILBENE | IC50 | = | 14050.0 | nM | 4.85 |
| CHEMBL2043273 | — | IC50 | = | 14150.0 | nM | 4.85 |
| CHEMBL2043272 | — | IC50 | = | 15290.0 | nM | 4.82 |
| CHEMBL2043275 | — | IC50 | = | 15550.0 | nM | 4.81 |
| CHEMBL383273 | — | IC50 | = | 15610.0 | nM | 4.81 |
| CHEMBL2043277 | — | IC50 | = | 16510.0 | nM | 4.78 |
| CHEMBL2043279 | — | IC50 | = | 17010.0 | nM | 4.77 |
| CHEMBL1817794 | — | IC50 | = | 17370.0 | nM | 4.76 |
| CHEMBL1817800 | — | IC50 | = | 18260.0 | nM | 4.74 |
| CHEMBL1817790 | — | IC50 | = | 19870.0 | nM | 4.70 |
| CHEMBL1817793 | — | IC50 | = | 21280.0 | nM | 4.67 |
| CHEMBL2043278 | — | IC50 | = | 21980.0 | nM | 4.66 |
| CHEMBL1817791 | — | IC50 | = | 23630.0 | nM | 4.63 |
| CHEMBL1817804 | — | IC50 | = | 24070.0 | nM | 4.62 |
| CHEMBL1817796 | — | IC50 | = | 25610.0 | nM | 4.59 |
| CHEMBL1817801 | — | IC50 | = | 26570.0 | nM | 4.58 |
| CHEMBL1817806 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2043280 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL1817802 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL165 | RESVERATROL | IC50 | > | 30000.0 | nM | - |